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HEIDELBERG UNIVERSITY

Doris Höglinger 
Lipid signaling and lysosomal biology

Groupleader: Doris Höglinger

2017
Höglinger D, Nadler A, Haberkant P, Kirkpatrick J, Schifferer M, Stein F, Hauke S, Porter FD, Schultz C. Trifunctional lipid probes for comprehensive studies of single lipid species in living cells. PNAS 2017; 114; 7; 1566-1571; doi: 10.1073/pnas.1611096114

2016
Fineran P, Lloyd-Evans E, Lack NA, Platt N, Davis LC, Morgan AJ, Höglinger D, Tatituri RV, Clark S, Williams IM, Tynan P, Al Eisa N, Nazarova E, Willians A, Galione A, Ory DS, Besra GS, Russell DG, Brenner MB, Sim E, Platt FM. Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway. Wellcome Open Res 2016; 1;18; doi: 10.12688/wellcomeopenres.10036.1.
 
Haberkant P, Stein F, Höglinger D, Gerl MJ, Brügger B, Van Veldhoven PP, Krijgsveld J, Gavin AC, Schultz C. Bifunctional sphingosine for cell-based analysis of proteins-sphingolipid interactions. ACS Chem Biol 2016; 11; 222-230

2015
Höglinger D, Haberkant P, Aguilera-Romero A, Riezman H, Porter FD, Platt FM, Galione A, Schultz C. Intracellular sphingosine releases calcium from lysosomes. ELife 2015; doi: 10.7554/eLife.10616
 
2014
Höglinger D, Nadler A, Schultz C. Caged lipids as tools for investigating cellular signaling. Biochim Biophys Acta 2014; 1841; 1085-1096
  
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