SFB 638 Projects
A 1: Mechanism of action of ribosome-associated chaperones in
co-translational folding and transport of proteins
Principal investigators:Prof. Dr. Bernd Bukau, ZMBH, Heidelberg
bukau@zmbh.uni-heidelberg.de
Dr. Günter Kramer, ZMBH, Heidelberg
g.kramer@zmbh.uni-heidelberg.de
Homepage
A 3: Structure and dynamics of protein/RNA complexes in
SRP-meditated protein transport
Principal investigators:Prof. Dr. Irmgard Sinning, BZH, Heidelberg
irmi.sinning@bzh.uni-heidelberg.de
Dr. Klemens Wild, BZH, Heidelberg
klemens.wild@bzh.uni-heidelberg.de
Homepage
A 5: Biogenesis, structure and dynamics of flaviviral
replication complexes
Principal investigator: Prof. Dr. Ralf Bartenschlager, Uniklinikum, Heidelbergralf_bartenschlager@med.uni-heidelberg.de
Homepage
A 8: Unconventional protein secretion
Principal investigator: Prof. Dr. Walter Nickel, BZH, Heidelbergwalter.nickel@bzh.uni-heidelberg.de
Homepage
A 9: Formation and dynamic alterations of retroviral transport, assembly
and budding complexes
Principal investigator: Prof. Dr. med. Hans-Georg Kräusslich, Uniklinikum, Heidelberghans-georg.kraeusslich@med.uni-heidelberg.de
Homepage
A 10: Dynamics of COPI assembly
Principal investigators:Dr. Britta Brügger, BZH, Heidelberg
britta.bruegger@bzh.uni-heidelberg.de
Prof. Dr. Felix Wieland, BZH, Heidelberg
felix.wieland@bzh.uni-heidelberg.de
Homepage
A 11: Modulation of architecture and function of the immunological
synapse by the HIV pathogenesis factor Nef
Principal investigator: Dr. Oliver Fackler, Uniklinikum, Heidelbergoliver.fackler@med.uni-heidelberg.de
Homepage
A 13: Mechanism and dynamics of Hsp70- and Hsp90-assisted
folding of transcription factors and kinases
Principal investigator: Dr. Matthias Mayer, ZMBH, Heidelbergm.mayer@zmbh.uni-heidelberg.de
Homepage
A 16: Structural dynamics of coatomer (from January 2008)
Principal investigators:Dr. John Briggs, EMBL, Heidelberg
briggs@embl.de
Prof. Dr. Felix Wieland, BZH, Heidelberg
felix.wieland@bzh.uni-heidelberg.de
Homepage Briggs
Homepage Wieland
A 18: Structure and dynamics of the protein O-mannosylation
machinery (from January 2008)
Principal investigator: Prof. Dr. Sabine Strahl, COS, Heidelbergsabine.strahl@cos.uni-heidelberg.de
Homepage
A 19: Structure and dynamics of protein complexes in tail-anchored
membrane protein biogenesis (from January 2012)
Principal investigator: Prof. Dr. Irmgard Sinning, BZH, Heidelbergirmi.sinning@bzh.uni-heidelberg.de
Homepage
B 2: Structure, function and reconstitution of the nuclear pore complex
Principal investigators:Dr. Dirk Flemming, BZH, Heidelberg
dirk.flemming@bzh.uni-heidelberg.de
Prof. Dr. Ed Hurt, BZH, Heidelberg
ed.hurt@bzh.uni-heidelberg.de
Homepage
B 3: Formation, maturation and nuclear export of mRNPs
Principal investigator: Prof. Dr. Ed Hurt, BZH, Heidelberged.hurt@bzh.uni-heidelberg.de
Homepage
B 4: Temporal and spatial dynamics of the circadian clock
of Neurospora
Principal investigator: Prof. Dr. Michael Brunner, BZH, Heidelbergmichael.brunner@bzh.uni-heidelberg.de
Homepage
B 7: Nuclear envelope insertion of the yeast centrosome
(from January 2008)
Principal investigator: Prof. Dr. Elmar Schiebel, ZMBH, Heidelbergschiebel.elmar@zmbh.uni-heidelberg.de
Homepage
B 8: Sumoylation of nuclear transport receptors (from January 2012)
Principal investigator: Prof. Dr. Frauke Melchior, ZMBH, Heidelbergfrauke.melchior@zmbh.uni-heidelberg.de
Homepage
B 9: Coupling of RNA quality control to nuclear export
(from January 2012)
Principal investigator: Dr. Tamás Fischer, BZH, Heidelbergtamas.fischer@bzh.uni-heidelberg.de
Homepage
Z 1: Protein analysis by mass spectrometry
Principal investigators:PD Dr. Johannes Lechner, BZH, Heidelberg
johannes.lechner@bzh.uni-heidelberg.de
Dr. Thomas Ruppert, ZMBH, Heidelberg
t.ruppert@zmbh.uni-heidelberg.de
Homepage Lechner
Homepage Ruppert
Z 2: Central Tasks
Principal investigator (Chairman of the SFB 638): Prof. Dr. Felix Wieland, BZH, Heidelbergfelix.wieland@bzh.uni-heidelberg.de
Z 3: Flow cytometry / Fluorescence-Activated Cell Sorting (FACS)
(from January 2008)
Principal investigator: Prof. Dr. Victor Sourjik, ZMBH, Heidelbergv.sourjik@zmbh.uni-heidelberg.de
Homepage
Z 4: HTP-Protein crystallization platform and X-ray structure
determination (from January 2012)
Principal investigator: Prof. Dr. Irmgard Sinning, BZH, Heidelbergirmi.sinning@bzh.uni-heidelberg.de
Homepage
Former Projects:
A 2: Signal peptides and the insertion of proteins into
the membrane of the endoplasmatic reticulum
(terminated on January 1st, 2012)
Principal investigator: Prof. Dr. Bernhard Dobbersteinnow: Professor emeritus, email: dobberstein@zmbh.uni-heidelberg.de
A 4: Mechanism and regulation of Arginine-signal mediated ER
localization(terminated on January 1st, 2008)
Principal investigator: Dr. Blanche Schwappach,now: Senior Lecturer of the Faculty of Life Sciences, University of Manchester
A 7: Biogenesis of peroxisomes (terminated on January 1st, 2008)
Principal investigator: Prof. Dr. Wilhelm Just, BZH, Heidelbergnow: Professor emeritus, email: wilhelm.just@bzh.uni-heidelberg.de
A 15: Coordination and regulation of yeast homotypic vacuole fusion;
mechanism and function of palmitoylation of fusion factors
(terminated on January 1st, 2006)
Principal investigator: Prof. Dr. Christian Ungermann,now: Speaker of the SFB 944, University of Osnabrück
B 1: Transport between nucleus and cytoplasm
(terminated on January 1st, 2008)
Principal investigator: Prof. Dr. Dirk Görlich,now: Director of the Max-Planck-Institut für biophysikalische Chemie, Göttingen
B 5: Regulation of complexes involved in spindle positioning
(Junior Research Group funded from October 2005 to September 2010)
Principal investigator: Dr. Dimitris Liakopoulos,now: still at the BZH, Heidelberg, E-Mail:dimitris.liakopoulos@bzh.uni-heidelberg.de
Former principal investigators:
Dr. Elke Deuerling, TP A1
(from January 2004 - March 2007)
now: Professor, University of Konstanz, Department of Biologyemail: elke.deuerling@uni-konstanz.de
Dr. Alwin Köhler, TP B3
(from Januaray 2008 - December 2009)
now: Junior Group Leader, Max F. Perutz Laboratories, Vienna, Austriaemail: alwin.koehler@univie.ac.at
Dr. Susana Rodriguez-Navarro, TP B3
(from January - April 2004)
now: Group Leader, Prince Felipe Research Centre (CIPF), Valenciaemail: srodriguez@cipf.es
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