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HEIDELBERG UNIVERSITY

SFB 638 Projects and PIs

 

 
Project
Title
Field of research Principal investigator(s), institute,
location

 
Duration of tenure
A Biosynthetic transport from the ribosome to the endomembrane system
 
A1 Mechanism of action of ribosome-associated chaperones in co-translational folding and transport of proteins Molecular Biology,
Biochemistry
Bukau, Bernd
Deuerling, Elke (01/2004 - 03/2007)
Kramer, Günter (04/2007 – 12/2015)
ZMBH Heidelberg
 
2004 - 2015
A2 Signal peptides and the insertion of tail-anchored (TA) proteins into the membrane of the endoplasmic reticulum
 
Cell Biology Dobberstein, Bernhard
ZMBH Heidelberg
2004 - 2011
A3 Structure and dynamics of protein/RNA complexes in SRP-mediated protein transport Protein Crystallography, Structural Biology, Biochemistry
 
Sinning, Irmgard
Wild, Klemens (01/2012 – 12/2015)
BZH Heidelberg
 
2004 - 2015
A4 Mechanism and regulation of Arginine-signal mediated ER localization Biochemistry, Molecular Cell Biology Schwappach, Blanche
ZMBH
Heidelberg
 
2004 - 2007
A5 Biogenesis, structure and dynamics of flaviviral replication complexes Molecular and Cellular Biology of Dengue Virus Replication and Assembly
 
Bartenschlager, Ralf Medizinische Fakultät Heidelberg 2004 - 2015
A7 Biogenesis  of  peroxisomes Biochemistry, Molecular Cell Biology
 
Just, Wilhelm
BZH Heidelberg
2004 - 2007
A8 Unconventional protein secretion Molecular Cell Biology, Biochemistry
 
Nickel, Walter
BZH Heidelberg
2004 - 2015
A9 Formation and dynamic alterations of retroviral transport, assembly and budding complexes Virology, Cell Biology Kräusslich,
Hans-Georg
Medizinische Fakultät Heidelberg
 
2004 - 2015
A10 Dynamics of COPI assembly Cell Biology, Biochemistry Brügger, Britta
Wieland, Felix T.
BZH Heidelberg
 
2004 - 2015
A11 Modulation of architecture and function of the immunological synapse by the HIV pathogenesis factor Nef
 
Virology, Cell Biology Fackler, Oliver T. Medizinische
Fakultät Heidelberg
2004 - 2015
A13 Mechanism and dynamics of Hsp70- and Hsp90-assisted folding of eukaryotic transcription factors and kinases
 
Molecular Biology, Biochemistry, Biophysics Mayer, Matthias Peter
ZMBH Heidelberg
2004 - 2015
A15 Coordination and regulation of the homotypic fusion of yeast vacuoles; mechanism and function of the palmitoylation of fusion factors
 
Biochemistry, Molecular Cell Biology Ungermann, Christian
BZH Heidelberg
2004 - 2005
Some PhD-projects are continued in the SFB 431 of the University of Osnabrück.
A16 Structural dynamics of coatomer
 
Structural Biology, Membrane Traffic
 
Briggs, John
EMBL Heidelberg
Wieland, Felix T.
BZH Heidelberg
 
2008 - 2015
A18 Structure and dynamics of the protein
O-mannosylation machinery
 
Biochemistry,
Glycobiology,
Molecular
Biology
 
Strahl, Sabine
COS Heidelberg
2008 - 2015
A19 Structure and dynamics of protein complexes in tail-anchored membrane protein biogenesis
 
Cell Biology
 
Sinning, Irmgard Maria
BZH Heidelberg
2012 - 2015
B The transport between nucleus and cytoplasm
 
B1 Transport between nucleus and cytoplasm
 
Molecular Cell Biology Görlich, Dirk
ZMBH Heidelberg
2004 - 2007
B2 Structure, function and reconstitution of the nuclear pore complex Biochemistry,
Molecular Cell Biology, Structural Biology
Hurt, Ed
Flemming, Dirk
(01/2012 – 12/2015
BZH Heidelberg
 
2004 - 2015
B3 Formation, maturation and nuclear export of mRNPs Biochemistry,
Molecular Cell
Biology, Structural Biology
Hurt, Ed
Rodriguez-Navarro, Susana (01/2004 – 04/2004)
Köhler, Alwin (01/2008 – 12/2009)
BZH Heidelberg
 
2004 - 2015
B4 Temporal and spatial dynamics of the circadian clock of Neurospora
 
Biochemistry Brunner, Michael
BZH Heidelberg
2004 - 2015
B5 Regulation of complexes involved in spindle positioning
 
Biochemistry,
Cell Biology
Liakopoulos, Dimitris
BZH Heidelberg
 
10/2005 – 09/2010
(Junior Research Group)
B7 Nuclear envelope insertion of the yeast centrosome Cdc14, Cell Cycle Regulation,
Spindle Assembly, Spindle Pole Body,
Human Centrosome Duplication
 
Schiebel, Elmar
ZMBH Heidelberg
2008 - 2015
B8
 
Sumoylation of nuclear transport receptors
 
Biochemistry, Cell Biology,
 Posttranslational Modification, Ubiquitin Related Proteins, SUMO,
Nucleocytoplasmic Transport
 
Melchior, Frauke
ZMBH Heidelberg
2012 - 2015
B9
 
Coupling of RNA quality control to nuclear export Biochemistry,
Molecular Cell Biology
 
Fischer,Tamás
BZH Heidelberg
2012 - 2015
Z1 Protein analysis by mass spectrometry Bioanalytic Research Lechner, Johannes
BZH Heidelberg
Ruppert, Thomas
ZMBH Heidelberg
 
2004-2015
Z2 Central tasks - administration
 
  Wieland, Felix T.
BZH Heidelberg
2004 - 2015
Z2
Lump sum funds
Role of COPI transport vesicles in mRNA localization and regulation Molecular Cell Biology Béthune, Julien
BZH Heidelberg
07/2013 – 12/2015
(Junior Research Group)
 
Z3 Flow Cytometry/Fluorescence Activated Cell Sorting (FACS) Cell Biology,
Molecular Biology
Sourjik, Victor
(01/2008 – 10/2013)
Knop, Michael
(11/2013 – 12/2015)
ZMBH Heidelberg
 
2008 - 2015
Z4
 
HTP-Protein crystallization platform and X-ray structure determination
 
Structural Biology Sinning, Irmgard Maria
BZH Heidelberg
2012 - 2015


New Positions of PIs:

A 2: Signal peptides and the insertion of proteins into
       the membrane of the endoplasmatic reticulum
      (terminated on January 1st, 2012)

Principal investigator: Prof. Dr. Bernhard Dobberstein
now: Professor emeritus


A 4: Mechanism and regulation of Arginine-signal mediated ER
       localization(terminated on January 1st, 2008)

Principal investigator: Dr. Blanche Schwappach,
now: University Medical Center Göttingen


A 7: Biogenesis of peroxisomes (terminated on January 1st, 2008)

Principal investigator: Prof. Dr. Wilhelm Just, BZH, Heidelberg
now: Professor emeritus


A 15: Coordination and regulation of yeast homotypic vacuole fusion;
         mechanism and function of palmitoylation of fusion factors
        (terminated on January 1st, 2006)

Principal investigator: Prof. Dr. Christian Ungermann,
now: Speaker of the SFB 944, University of Osnabrück


B 1: Transport between nucleus and cytoplasm
(terminated on January 1st, 2008)

Principal investigator: Prof. Dr. Dirk Görlich,
now: Director of the Max-Planck-Institut für biophysikalische Chemie, Göttingen


B 5: Regulation of complexes involved in spindle positioning
(Junior Research Group funded from October 2005 to September 2010)

Principal investigator: Dr. Dimitris Liakopoulos,
now: Centre de Recherche de Biochimie Macromoléculaire, Montpellier
 

Dr. Elke Deuerling, TP A1
(from January 2004 - March 2007)

now: Professor, University of Konstanz, Department of Biology
 

Dr. Alwin Köhler, TP B3
(from Januaray 2008 - December 2009)

now: Junior Group Leader, Max F. Perutz Laboratories, Vienna, Austria
 

Dr. Susana Rodriguez-Navarro, TP B3
(from January - April 2004)

now: Group Leader, Prince Felipe Research Centre (CIPF), Valencia
 

Prof. Dr. Victor Sourjik, TP Z3
(from January 2012 - October 2013)

now: Max-Planck-Institute of Terrestrial Microbiology in Marburg



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