In the lab, we are using a multidisciplinary approach to investigate proteins and protein complexes with essential functions during germ cell formation and early embryonic development. The research focusses on molecular mechanism such as piRNA-mediated transposon silencing and translation control of mRNAs, which are essential during early animal development.
In particular, we are currently focusing ours studies on LOTUS domain-containing proteins and on RNA helicases. To unravel the molecular mechanisms of how these proteins function, we employ a multidisciplinary approach combining RNA/protein biochemistry, X-ray crystallography, cell culture techniques as well as Drosophila genetics.
1998 - 2005
Biochemistry Studies at University Halle-Wittenberg
2005 - 2010
PhD at the University Halle-Wittenberg with Elmar Wahle
2010 - 2017
Postdoc at the EMBL with Anne Ephrussi and Christoph W. Müller
(EIPOD Developmental/Structural biology)
Emmy Noether Group Leader at the Heidelberg University Biochemistry Center (BZH)