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Complete List of Publications
https://orcid.org/0000-0001-8158-9301Selected Publications
Köhler S, Peschek J (2025) Interdomain assembly between the fungal tRNA ligase adenylyltransferase and kinase domain. RNA. doi: 10.1261/rna.080592.125. Epub ahead of print.
Guo W, Kaczmarczyk I, Kopietz K, Flegler F, Russo S, Cigirgan E, Chramiec-Głąbik A, Koziej Ł, Cirzi C, Peschek J, Reuter K, Helm M, Glatt S, Tuorto F (2025) Queuosine is incorporated into precursor tRNA before splicing. Nat Commun. 16:7044.
Köhler S, Kopp J, Maiti S, Bujnicki JM, Peschek J (2025) Structure of fungal tRNA ligase Trl1 with RNA reveals conserved substrate-binding principles. Nat Struct Mol Biol.
Gerber JL, Morales Guzmán SI, Worf L, Hubbe P, Kopp J, Peschek J (2024) Structural and mechanistic insights into activation of the human RNA ligase RTCB by Archease. Nat Commun. 15:2378
Li W*, Crotty K*, Garrido Ruiz D, Voorhies M, Rivera C, Sil A, Mullins RD, Jacobson MP, Peschek J§, Walter P§ (2021) Protomer alignment modulates specificity of RNA substrate recognition by Ire1. eLife 10:e67425
Peschek J§ & Walter P§ (2019) tRNA ligase structure reveals kinetic competition between non-conventional mRNA splicing and mRNA decay. eLife 8:e44199.
Li W, Okreglak V, Peschek J, Kimmig P, Zubradt M, Weissman JS, Walter P (2018) Engineering ER-stress dependent non-conventional mRNA splicing. eLife 7: e35388.
Peschek J*, Acosta-Alvear D*, Mendez AS, Walter P (2015) A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing. EMBO Rep. 16(12):1688-98.
Mainz A, Peschek J, Stavropoulou M, Back KC, Bardiaux B, Asami S, Prade E, Peters C, Weinkauf S, Buchner J, Reif B (2015) The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid client. Nat Struct Mol Biol. 22(11):898-905.
Feige MJ, Gräwert MA, Marcinowski M, Hennig J, Behnke J, Ausländer D, Herold EM, Peschek J, Castro CD, Flajnik M, Hendershot LM, Sattler M, Groll M, Buchner J (2014) The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins. PNAS 111(22):8155-60.
Peschek J, Braun N, Rohrberg J, Back KC, Kriehuber T, Kastenmüller A, Weinkauf S, Buchner J (2013) Regulated structural transitions unleash the chaperone activity of αB-crystallin. PNAS 110(40):E3780-9.
Müller R, Gräwert MA, Kern T, Madl T, Peschek J, Sattler M, Groll M, Buchner J (2013) High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation. PNAS 110(25):10183-8.
Drazic A, Miura H, Peschek J, Le Y, Bach NC, Kriehuber T, Winter J (2013) Methionine oxidation activates a transcription factor in response to oxidative stress. PNAS 110(23):9493-8.
Braun N, Zacharias M, Peschek J, Kastenmüller A, Zou J, Hanzlik M, Haslbeck M, Rappsilber J, Buchner J, Weinkauf S (2011) Multiple molecular architectures of the eye lens chaperone αB-crystallin elucidated by a triple hybrid approach. PNAS 108(51):20491-20496.
Peschek J*, Braun N*, Franzmann TM*, Georgalis Y, Haslbeck M, Weinkauf S, Buchner J (2009) The eye lens chaperone α-crystallin forms defined globular assemblies. PNAS 106(32):13272-13277.
Reviews and Method Papers
Peschek J, Tuorto F (2025) Interplay Between tRNA Modifications and Processing. J Mol Biol. 437(16):169198
JL Gerber*, S Köhler*, J Peschek (2022) Eukaryotic tRNA splicing–one goal, two strategies, many players. Biological Chemistry 403(8-9): 765-778.
Peschek J (2021) Mechanismen des nicht konventionellen RNA-Spleißens. BIOspektrum 27(3): 233–236
Karagöz GE, Peschek J, Walter P, Acosta-Alvear D (2019) In vitro RNA Cleavage Assays to Characterize IRE1-dependent RNA Decay. Bio-protocol 9(14):e3307.
Haslbeck M, Peschek, Buchner J, Weinkauf S (2016) Structure and function of α-crystallins: Traversing from in vitro to in vivo. Biochim Biophys Acta 1860(1 Pt B):149-66. [Review]
