Publications


ReLo: a simple colocalization assay to identify and characterize physical protein-protein interactions. BioRxiv. doi: https://doi.org/10.1101/2022.03.04.482790
 

Salgania, H.K., Metz, J., and Jeske, M. (2022)

RNA binding proteins Smaug and Cup induce CCR4-NOT-dependent deadenylation of the nanos mRNA in a reconstituted system. BioRxiv. doi:https://doi.org/10.1101/2022.05.11.491288
 

Pekovic, F., Rammelt, C., Kubíková, J., Metz, J., Jeske, M., Wahle, E. (2022)

A Role for Liquid-Ordered Plasma Membrane Nanodomains Coordinating the Unconventional Secretory Pathway of Fibroblast Growth Factor 2? Front Cell Dev Biol. 2022 Apr 1;10:864257.
doi: 10.3389/fcell.2022.864257. eCollection 2022.

Lolicato, F., Nickel, W. (2022)

Antibacterial peptide CyclomarinA creates toxicity by deregulating the Mycobacterium tuberculosis ClpC1-ClpP1P2 protease. J. Biol. Chem. 298:102202. doi: https://doi.org/10.1016/j.jbc.2022.102202.

Taylor, G., Frommherz, Y., Katikaridis, P., Layer, D., Sinning, I., Carroni, M., Weber-Ban, E. & Mogk, A. (2022)

Cryo-EM insights into tail-anchored membrane protein biogenesis in eukaryotes, Curr. Opin. Struct. Biol. 75: 102428. doi: https://doi.org/10.1016/j.sbi.2022.102428.

Sinning, I. and McDowell, M.A. (2022)

Glypican-1 drives unconventional secretion of Fibroblast Growth Factor 2. Elife. 2022 Mar 29;11:e75545. doi: 10.7554/eLife.75545. Online ahead of print.

Sparn, C., Dimou, E., Meyer, A., Saleppico, R., Wegehingel, S., Gerstner, M., Klaus, S., Ewers, H. & Nickel, W. (2022)

High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation, Nat Comms. 13: 476. https://doi.org/10.1038/s41467-022-27967-9..

Kišonaitė, M., Wild, K., Lapouge, K., Ruppert, T. & Sinning, I. (2022)

HYPK promotes the activity of the Nα-acetyltransferase A complex to determine proteostasis of nonAc-X2/N-degron-containing proteins, Sci. Adv. 8:eabn6153. doi: https://doi.org/10.1126/sciadv.abn6153.

Miklánková, P., Linster, E., Boyer, J.B., Weidenhausen, J., Mueller, J., Armbruster, L., Lapouge, K., De La Torre, C., Bienvenut, W., Sticht, C., Mann, M., Meinnel, T., Sinning, I., Giglione, C., Hell, R. & Wirtz, M. (2022)

Marzoll, D., Serrano, F., Shostak, A., Schunke, C., Diernfellner, A.C.R., Brunner, M. Casein kinase 1 and disordererd clock proteins form functionally equivalent, phospho-based circadian modules in fungi and mammals. PNAS 119, 9 https://doi.org/10.1073/pnas.2118286119

Michael Brunner (2022)

Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex, bioRxiv: https://www.biorxiv.org/content/10.1101/2022.07.20.500385v1, doi:https://doi.org/10.1101/2022.07.20.500385.

Soni, K., Sivadas, A., Horváth, A., Dobrev, N., Hayashi, R., Kiss, L., Simon, B., Wild, K. & Sinning*, I, Fischer*, T. (2022)

Reticulon-like REEP4 at the inner nuclear membrane promotes nuclear pore complex formation. J Cell Biol; 221 (2): e202101049. doi: https://doi.org/10.1083/jcb.20210104

Golchoubian, B., Brunner, A., Bragulat-Teixidor, H., Neuner, A., Akarlar, B.A., Ozlu, N. & Schlaitz, A.L. (2022)

Singh A, Li C, Diernfellner ACR, Höfer T, Brunner M. Data-driven modelling captures dynamics of the circadian clock of Neurospora crassa. PLoS Comput Biol. 2022 Aug 11;18(8):e1010331. doi: 10.1371/journal.pcbi.1010331. PMID: 35951637; PMCID: PMC9397904.

Michael Brunner (2022)

Structural inventory of cotranslational protein folding by the eukaryotic RAC complex, bioRxiv https://www.biorxiv.org/content/10.1101/2022.06.24.497458v1, doi: https://doi.org/10.1101/2022.06.24.497458.

Kišonaitė, M., Wild, K., Lapouge, K., Valentín Gesé, G., Kellner, N., Hurt, E. & Sinning, I. (2022)

Trim-Away degrades lysine-less substrates without requiring ligase autoubiquitination, bioRxiv: https://www.biorxiv.org/content/10.1101/2022.06.29.498105v1, doi: https://doi.org/10.1101/2022.06.29.498105.

Kiss, L., Rhinesmith, T., Dickson, C.F., Weidenhausen, J., Smyly, S., Luptak, J., Yang, J.C., Maslen, S.L., Sinning, I., Neuhaus, D., Clift, D. & James, L.C. (2022)

Unconventional secretion mediated by direct protein self-translocation across the plasma membranes of mammalian cells, Trends Biochem Sci. 2022 Apr 27;S0968-0004(22)00086-X.
doi: 10.1016/j.tibs.2022.04.001. Online ahead of print.

Sparn, C., Meyer, A., Saleppico, R., Nickel, W. (2022)

Unconventional secretion mediated by direct protein self-translocation across the plasma membranes of mammalian cells. Trends Biochem Sci. 2022 Apr 27;S0968-0004(22)00086-X.
doi: 10.1016/j.tibs.2022.04.001. Online ahead of print.

Sparn, C., Meyer, A., Saleppico, R., Nickel, W. (2022)

Molekulare Funktionen von Keimbahn-spezifischen Proteinen. BIOspektrum. 27, 101.

Jeske, M. (2021)

Molecular functions of germline proteins. EU Research. SPR21, 18.

Jeske, M. (2021)

Mechanismen des nicht konventionellen RNA-Spleißens. BIOspektrum 27(3): 233–236

Peschek, J. (2021)

A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis. Open biology, 11(11), 210250. https://doi.org/10.1098/rsob.210250

Zhang, W., Khan, A., Vitale, J., Neuner, A., Rink, K., Lüchtenborg, C., Brügger, B., Söllner, T. H., & Schiebel, E. (2021)

CaM Kinase II-δ Is Required for Diabetic Hyperglycemia and Retinopathy but Not Nephropathy. Diabetes; 70 (2): 616–626. doi: https://doi.org/10.2337/db19-0659

Chen, J., Fleming, T., Katz, S., Dewenter, M., Hofmann, K., Saadatmand, A., Kronlage, M., Werner, M.P., Pokrandt, B., Schreiter, F., Lin, J., Katz, D., Morgenstern, J., Elwakiel, A., Sinn, P., Gröne, H.J., Hammes, H.P., Nawroth, P.P., Isermann, B., Sticht, C., Brügger, B., Katus, H.A., Hagenmueller, M. & Backs, J. (2021)

Cellular cholesterol and how to find it. Cellular cholesterol and how to find it. Biochim Biophys Acta Mol Cell Biol Lipids. 1866(9):158989. https://doi.org/10.1016/j.bbalip.2021.158989

Schoop, V., Martello, A., Eden, E.R., & Höglinger, D. (2021)

Cholesterol promotes both head group visibility and clustering of PI(4,5)P2 driving unconventional secretion of Fibroblast Growth Factor 2. https://www.biorxiv.org/content/10.1101/2021.04.16.440132v1

Lolicato, F., Saleppico, R., Griffo, A., Pokrandt, B., Müller, H.M., Ewers, H, Hähl, H, Fleury, J.P., Seemann, R., Brügger, B., Jacobs, K., Vattulainen, I. & Nickel, W. (2021)

Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation. Nat Commun 12, 7276. https://doi.org/10.1038/s41467-021-27511-1

Tabata, K., Prasad, V., Paul, D., Lee, J.Y., Pham, M.T., Twu, W.I., Neufeldt, C.J., Cortese, M., Cerikan, B., Stahl, Y., Joecks, S., Tran, C.S., Lüchtenborg, C., V'kovski, P., Hörmann, K., Müller, A.C., Zitzmann, C., Haselmann, U., Beneke, J., Kaderali, L., Erfle, H., Thiel, V., Lohmann, V., Superti-Furga, G., Brügger, B. & Bartenschlager, R. (2021)

Cooperativity of membrane-protein and protein–protein interactions control membrane remodeling by epsin 1 and affects clathrin-mediated endocytosis. Cell. Mol. Life Sci. 78, 2355–2370. https://doi.org/10.1007/s00018-020-03647-z. PDF.

Kroppen, B., Teske, N., Yambire, K., Denkert, N., Mukherjee, I., Tarasenko, D., Jaipura, G., Zweckstetter, M., Milosevic, I., Steinem, C. & Meinecke, M. (2021)

DEAD-box RNA helicases act as nucleotide exchange factors for casein kinase 2, bioRxiv: https://www.biorxiv.org/content/10.1101/2021.12.20.473452v1. doi: https://doi.org/10.1101/2021.12.20.473452.

Fatti, E., Hirth, A., Švorinić, A., Günther, M., Cruciat, C.M., Stier, G., Acebron, S.P., Papageorgiou, D., Sinning, I., Krijgsveld, J., Höfer , T. & Niehrs, C. (2021)

ENTH domain-dependent membrane remodelling. ENTH domain-dependent membrane remodelling. Soft matter, 17(2), 233–24. https://doi.org/10.1039/C9SM02437A

Steinem C. & Meinecke M. (2021)

Global Transcriptome Characterization and Assembly of the Thermophilic Ascomycete Chaetomium thermophilum. Genes 12, 1549. https://doi.org/10.3390/genes12101549

Singh, A., Schermann, G., Reislöhner, S., Kellner, N., Hurt, E., & Brunner, M. (2021)

Ice2 promotes ER membrane biogenesis in yeast by inhibiting the conserved lipin phosphatase complex. The EMBO Journal 40: e107958. https://doi.org/10.15252/embj.2021107958

Papagiannidis, D., Bircham, P.W., Lüchtenborg, C., Pajonk, O., Ruffini, G., Brügger, B. & Schuck, S. (2021)

Identification of cis-acting determinants mediating the unconventional secretion of tau. Sci Rep 11, 12946. https://doi.org/10.1038/s41598-021-92433-3

Katsinelos, T., McEwan, W.A., Jahn, T.R. & Nickel, W. (2021)

Inositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites. Nat Commun 12, 2673. https://doi.org/10.1038/s41467-021-22882-x

Malek, M., Wawrzyniak, A.M., Koch, P., Lüchtenborg, C., Hessenberger, M., Sachsenheimer, T., Jang, W., Brügger, B. & Haucke, V. (2021)

Metabolic memory underlying minimal residual disease in breast cancer. Mol Syst Biol. 17: e10141. https://doi.org/10.15252/msb.202010141

Radic, S.hechter, K., Kafkia, E., Zirngibl, K., Gawrzak, S., Alladin, A., Machado, D., Lüchtenborg, C., Sévin, D.C., Brügger, B., Patil, K.R. & Jechlinger, M. (2021)

MICOS and the mitochondrial inner membrane morphology – when things get out of shape. FEBS Lett, 595: 1159-1183. https://doi.org/10.1002/1873-3468.14089

Mukherjee, I., Ghosh, M. & Meinecke, M. (2021)

Principles of membrane remodeling by dynamic ESCRT-III polymers. Trends Cell Biol 31(10), 856-868. https://doi.org/10.1016/j.tcb.2021.04.005

Pfitzner, A.-K., Moser von Filseck, J., & Roux, A. (2021)

Protein-dependent membrane remodeling in mitochondrial morphology and clathrin-mediated endocytosis. European biophysics journal : EBJ, 50(2), 295–306. https://doi.org/10.1007/s00249-021-01501-z

Tarasenko, D. & Meinecke, M. (2021)

Protomer alignment modulates specificity of RNA substrate recognition by Ire1. eLife, 10. http://doi.org/10.7554/eLife.67425

Li, W.*, Crotty, K.*, Garrido Ruiz, D., Voorhies, M., Rivera, C., Sil, A., Mullins, R.D., Jacobson, M.P., Peschek, J. & Walter, P. (2021)

Public LC-orbitrap tandem mass spectral library for metabolite identification. Journal of Proteome Research, 20. https://doi.org/10.1021/acs.jproteome.0c00930

Phapale, P., Palmer, A., Gathungu, R.M., Kale, D., Brügger, B. & Alexandrov, T. (2021)

SRP54 mutations induce congenital neutropenia via dominant-negative effects on XBP1 splicing. Blood, 137(10), 1340–1352. https://doi.org/10.1182/blood.2020008115

Schürch, C., Schaefer, T., Müller, J. S., Hanns, P., Arnone, M., Dumlin, A., Schärer, J., Sinning, I., Wild, K., Skokowa, J., Welte, K., Carapito, R., Bahram, S., Konantz, M., & Lengerke, C. (2021)

Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins. Nature communications, 12(1), 4590. https://doi.org/10.1038/s41467-021-24844-9

Nůsková H, Serebryakova, M.V., Ferrer-Caelles, A., Sachsenheimer, T., Lüchtenborg, C., Miller, A.K., Brügger, B., Kordyukova, L.V. & Teleman, A.A. (2021)

Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation. Commun Biol 4, 600. https://doi.org/10.1038/s42003-021-02132-y

Soni, K., Kempf, G., Manalastas-Cantos, K., Hendricks, A., Flemming, D., Guizetti, J., Simon, B., Frischknecht, F., Svergun, D.I., Wild, K., & Sinning, I. (2021)

Structural and functional characterization of the N-terminal acetyltransferase Naa50. Structure, 29(5), 413–425.e5. https://doi.org/10.1016/j.str.2020.12.004

Weidenhausen, J., Kopp, J., Armbruster, L., Wirtz, M., Lapouge, K., & Sinning, I. (2021)

Structural and functional impact of SRP54 mutations causing severe congenital neutropenia. Structure, 29. doi: http://doi.org/10.1016/j.str.2020.09.008

Juaire, K.D., Lapouge, K., Becker, M.M.M., Kotova, I., Michelhans, M., Carapito, R., Wild, K., Bahram, S. & Sinning, I. (2021)

Structural and molecular mechanisms for membrane protein biogenesis by the Oxa1 superfamily. Nat Struct Mol Biol 28, 234–239. https://doi.org/10.1038/s41594-021-00567-9

McDowell, M.A., Heimes, M. & Sinning, I. (2021)

Structural basis of Naa20 activity towards a canonical NatB substrate. Commun Biol 4, 2. https://doi.org/10.1038/s42003-020-01546-4

Layer, D., Kopp, J., Fontanillo, M., Köhn, M., Lapouge, K. & Sinning, I. (2021)

The glucosylceramide synthase inhibitor PDMP causes lysosomal lipid accumulation and mTOR inactivation. Int J Mol Sci, 22(13):7065. doi: https://doi.org/10.3390/ijms22137065

Harwig, P. & Höglinger, D. (2021)

The inner nuclear membrane protein Lem2 coordinates RNA degradation at the nuclear periphery. bioRxiv https://www.biorxiv.org/content/10.1101/2021.05.30.446327v1, doi: https://doi.org/10.1101/2021.05.30.446327.

Caballero, L.M., Capella, M., Barrales, R.R., Dobrev, N., van Emden, T., Fischer-Burkart, S., Kinugasa, Y., Hirano, Y., Sinning, I., Fischer, T., Hiraoka, Y. & Braun, S. (2021)

The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain. Nat Comms. 12: 3456. PMID: 34103492. doi: https://doi.org/10.1038/s41467-021-23565-3

Dobrev, N., Ahmed, Y.L., Sivadas, A., Fischer*, T. & Sinning*, I. (2021)

90S pre-ribosome transformation into the primordial 40S subunit.
Reprint
Science369, 1470-1476.

Cheng J, Lau B, La Venuta G, Ameismeier M, Berninghausen O, Hurt E, Beckmann R. (2020)

LOTUS-domain proteins - Developmental effectors from a molecular perspective. Biol. Chem. 402, 7–23.

Kubíková, J., Reinig, R., Salgania, H.K., and Jeske, M. (2020)

Cellular senescence and quiescence are associated with altered ribosomal RNA methylation and processing. BioRxiv doi: 10.1101/2020.04.01.019653.

Yang,G., Heisenberger,C., Polacek,N., Grillari,J., Schosserer,M. and Koš,M. (2020)

Modulation of mammalian translation by a ribosome associated tRNA half. RNA Biol 30:1-12, doi: 10.1080/15476286.2020.1744296.

Gonskikh,Y., Gerstl,M., Koš,M., Borth,N., Schosserer,M., Grillari,J. and Polacek,N. (2020)

A novel neurodegenerative spectrum disorder in patients with MLKL deficiency. Cell Death Dis. 11(5):303.

Faergeman SL, Evans H, Attfield KE, Desel C, Kuttikkatte SB, Sommerlund M, Jensen LT, Frokiaer J, Friese MA, Matthews PM, Lüchtenborg C, Brügger B, Oturai AB, Dendrou CA, Fugger L. (2020)

A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells. Life Science Alliance 3, e202000714. https://doi.org/10.26508/lsa.202000714

Jain Goyal, M., Zhao, X., Bozhinova, M., Andrade-López, K., de Heus, C., Schulze-Dramac, S., Müller-McNicoll, M., Klumperman, J., and Béthune, J. (2020)

An ESCRT-III Polymerization Sequence Drives Membrane Deformation and Fission. Cell 182, 1-16. https://doi.org/10.1016/j.cell.2020.07.021

Pfitzner A-K, Mercier V, Jiang X, Moser von Filseck J, Baum B, Šarić A and Roux A. (2020)

Anisotropic ESCRT-III architecture governs helical membrane tube formation. Nat Commun 11, 1516. https://doi.org/10.1038/s41467-020-15327-4

Moser von Filseck J, Barberi L, Talledge N, Johnson I, Frost A, Lenz M and Roux A. (2020)

Arrangements of proteins at reconstituted synaptic vesicle fusion sites depend on membrane separation. FEBS Letters, https://doi.org/10.1002/1873-3468.13916

Ginger L, Malsam M, Sonnen A, Morado D, Scheutzow A, Söllner TH, Briggs J (2020)

Atg21 organizes Atg8 lipidation at the contact of the vacuole with the phagophore. Autophagy https://doi.org/10.1080/15548627.2020.1766332

Munzel L., Neumann P., Otto F.B., Krick R., Metje-Sprink J., Kroppen B., Karedla N., Enderlein J., Meinecke M., Ficner R., Thumm M. (2020)

Cholesterol localization around the metabotropic glutamate receptor 2, J. Phys. Chem. B 24: 9061-9078. PMID: 32954729.

Kurth, M., Lolicato, F., Sandoval-Perez, A., Amaya-Espinosa, H., Teslenko, A., Sinning, I., Beck, R., Brügger B. & Aponte-Santamaria, C.A. (2020)

Complexin suppresses spontaneous exocytosis by capturing the membrane-proximal regions of VAMP2 and SNAP25. Cell Reports, 32. https://doi.org/10.1016/j.celrep.2020.107926

Malsam, J., Bärfuss, S., Trimbuch, T.h, Zarebidaki, F., Sonnen, A., Wild, K., Scheutzow, A., Rohland, L., Mayer, M., Sinning, I., Briggs, J., Rosenmund, C. & Söllner, T.H. (2020)

Construction of the Central Protuberance and L1 stalk during 60S subunit biogenesis Mol. Cell, doi.org/10.1016/j.molcel.2020.06.032.

Lukas Kater, Valentin Mitterer, Matthias Thoms, Jingdong Cheng, Otto Berninghausen, Roland Beckmann and Ed Hurt (2020)

Dynamic palmitoylation events following T-cell receptor signaling. Commun Biol. 3(1):368.

Morrison E, Wegner T, Zucchetti AE, Álvaro-Benito M, Zheng A, Kliche S, Krause E, Brügger B, Hivroz C, Freund C. (2020)

EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake. Proc Natl Acad Sci U S A. 117(13):7471-7481.

Matthaeus C, Lahmann I, Kunz S, Jonas W, Melo AA, Lehmann M, Larsson E, Lundmark R, Kern M, Blüher M, Olschowski H, Kompa J, Brügger B, Müller DN, Haucke V, Schürmann A, Birchmeier C, Daumke O. (2020)

ESCRT machinery mediates selective microautophagy of endoplasmic reticulum in yeast. EMBO Journal. (abstract)

Schäfer JA, Schessner JP, Bircham PW, Tsuji T, Funaya C, Pajonk O, Schaeff K, Ruffini G, Papagiannidis D, Knop M, Fujimoto T, Schuck S (2020)

ESCRTing endoplasmic reticulum to microautophagic degradation. Autophagy. Commentary (abstract)

Schäfer JA, Schuck S (2020)

FGF2 and IL-1β: Explorers of unconventional secrtory pathways. J Cell Sci 133(21):jcs250449.

Pallotta MT and Nickel W (2020)

Functional assay to correlate protein oligomerization states with membrane pore formation. Anal Chem 92(22):14861-14866.

Sachl R, Cujova S, Singh V, Riegerova P, Kapusta P, Müller HM, Steringer JP, Hof M and Nickel W (2020)

Functional implications of MIR domains in protein O-mannosylation, eLife 9: e61189. PMID: 33357379.

Chiapparino#, A., Grbavac#, A., Jonker, H.R.A., Hackmann, Y., Mortensen, S., Zatorska, E., Schott, A., Stier, G., Saxena, K., Wild, K., Schwalbe, H., Sabine Strahl*, S. & Sinning*, I. (2020)

Heme binding of transmembrane signaling proteins undergoing regulated intramembrane proteolysis. Commun Biol. 3(1):73.

Kupke T, Klare JP, Brügger B. (2020)

Hrd1 forms the retrotranslocation pore regulated by auto-ubiquitination and binding of misfolded proteins. Nature Cell Biology 22(3):274-281

Vasic V., Denkert N., Schmidt C., Riedel D., Stein A., Meinecke M. (2020)

Medusys. Ein kompetenzorientiertes Lernsystem für Lernende und Lehrende. So gelingt E-Learning. Reader zum Higher Education Summit 2019. Pearson: 132-137.
 

Merz WE (2020)

Membrane Biology: Disentangling Cellular Lipid Connections. Curr Biol. 30(19):R1090-R1092.

Brügger B. (2020)

MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments, Nat Comms. 11: 776. PMID: 32034140.

Wild, K., Aleksić, M., Lapouge, K., Juaire, K.D., Flemming, D., Pfeffer, S. & Sinning, I. (2020)

Microautophagy - distinct molecular mechanisms handle cargoes of many sizes. Journal of Cell Science. Review (abstract)

Schuck S (2020)

Multiple random phosphorylations in clock proteins provide long delays and switches. Sci Rep 10, 22224.

Upadhyay, A., Marzoll, D., Diernfellner, A., Brunner, M. and Herzel, H. (2020)

NAA50 is an enzymatically active Nα-acetyltransferase that is crucial for the development and regulation of stress responses, Plant Physiol. 183: 1502-1516.

Armbruster, L., Linster, E., Boyer, J.B., Brünje, A., Eirich, J., Stephan, I., Bienvenut, W.V., Weidenhausen, J., Meinnel, T., Hell, R., Sinning, I., Finkemeier, I., Giglione,G. & Wirtz, M. (2020)

N-terminal acetylation by NatB affects growth and abiotic stress responses in Arabidopsis, Plant Physiol. 182: 792-806. PMID: 31744933.

Huber, M., Bienvenut, W.V., Linster, E., Stephan, I., Armbruster, L., Sticht, C., Layer, D., Lapouge, K., Meinnel, T., Sinning, I., Giglione, C., Hell, R. & Wirtz, M. (2020)

Phosphorylation Timers in the Neurospora crassa Circadian Clock. J Mol Biol 432, 3449-3465.

Diernfellner, A. C. R., and Brunner, M. (2020)

PI(4,5)P2-dependent regulation of exocytosis by amisyn, the vertebrate-specific competitor of synaptobrevin 2. PNAS https://doi.org/10.1073/pnas.1908232117

Kondratiuk I, Jakhanwal S, Jin J, Sathyanarayanan U, Kroppen B, Pobbati A, Krisko A, Ashery U, Meinecke M, Jahn R, Fasshauer D, Milosevic I. (2020)

Protease-resistant streptavidin for interaction proteomics. Molecular Systems Biology, 16: e9370. https://doi.org/10.15252/msb.20199370

Rafiee, M.-R., Sigismondo, G., Kalxdorf, M., Förster, L.-C., Brügger, B., Béthune, J., & Krijgsveld, J (2020)

Structural basis for the complex DNA binding behaviour of the plant stem cell regulator WUSCHEL, Nat. Comms. 11: 2223. PMID: 32376862.

Sloan, J., Hakenjos, J.P., Gebert, M., Ermakova, O., Gumiero, A., Stier, G., Wild, K., Sinning*, I. & Lohmann*, J.U. (2020)

Structural basis of tail-anchored membrane protein biogenesis by the GET insertase complex, Mol Cell 80: 72-86.e7. PMID: 32910895.

McDowell*, M.A., Heimes, M., Fiorentino, F., Mehmood, S., Farkas, Á., Coy-Vergara, J., Wu, D., Schmid, V., Heinze, R., Reddy Bolla, J., Wild, K., Flemming, D., Pfeffer, S., Schwappach, B., Robinson, C.V. & Sinning*, I. (2020)

Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome. Mol. Cell .

Benjamin Lau, Jingdong Cheng, Dirk Flemming, Giusseppe La Venuta, Otto Berninghausen, Roland Beckmann and Ed Hurt (2020)

The Arabidopsis Nα-acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response, New Phytologist, doi: 10.1111/nph.16747. Online ahead of print. PMID: 32548857

Linster#, E., Layer#, D., Bienvenut, W.V., Dinh-Van, T., Weyer, F., Lemhuis, W., Brünje, A., Hoffrichter, M., Miklankova, P., Sindlinger, J., Schwarzer, D., Kopp, J., Lapouge, K., Meinnel, T., Giglione, C., Finkemeier, I., Hell, R., Sinning*, I. & Wirtz*, M. (2020)

The endoplasmatic reticulum during mitosis. Biospektrum 26:739-742. (in German)

Schlaitz AL (2020)

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Defining the structural requirements for ribose 5-phosphate-binding and intersubunit cross-talk of the malarial pyridoxal 5-phosphate synthase. FEBS Lett. 584(19):4169-74.

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Distinct Roles of Myosin Va in Membrane Remodeling and Exocytosis of Secretory Granules. Traffic, 11: 637-650.

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Molecular genetics evidence for the in vivo roles of the two major NADPH-dependent disulfide reductases in the malaria parasite. J Biol Chem. 285(48):37388-95.

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Photoadaptation in Neurospora by competitive interaction of activating and inhibitory LOV domains. Cell 142, 762-772.

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Precise mapping of subunits in multiprotein complexes by a versatile EM-label. Nature Struct. Mol. Biol. in press.

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Dieter Kressler, Daniela Roser, Brigitte Pertschy and Ed Hurt (2008)

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Alwin Köhler, Maren Schneider, Ghislain Cabal, Ulf Nehrbass and Ed Hurt (2008)

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Guidance of Vascular and Neuronal Network Formation. Book chapter for the book titled “Tumor angiogenesis: Mechanisms and Cancer therapy”. Edited by Marmé, Fusenig and Norbert. Springer 2007: 47-65. (*These authors contributed equally)

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Philipp Stelter, Ruth Kunze, Dirk Flemming, Dominic Höpfner, Meikel Diepholz, Peter Philipsen, Bettina Böttcher and Ed Hurt (2007)

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Wei Yao, Daniela Roser, Alwin Köhler, Bettina Bradatsch, Jochen Baßler and Ed Hurt (2007)

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Wiese S, Gronemeyer T, Ofman R, Kunze M, Grou CP, Almeida JA, Eisenacher M, Stephan C, Hayen H, Schollenberger L, Korosec T, Waterham HR, Schliebs W, Erdmann R, Berger J, Meyer HE, Just W, Azevedo JE, Wanders RJ, Warscheid B. (2007)

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Schuck S*, Gerl MJ*, Ang AL, Manninen A, Keller P, Mellman I, Simons K (2007)

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Structural and Thermodynamic Insights into the Assembly of the Heteromeric Pyridoxal Phosphate Synthase from Plasmodium falciparum. J Mol Biol. 374:732-48.

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The C. elegans RSA complex localizes protein phosphatase 2A to centrosomes and regulates mitotic spindle assembly. Cell 128:115-127.

Schlaitz AL, Srayko M, Dammermann A, Quintin S, Wielsch N, MacLeod I, de Robillard Q, Zinke A, Yates JR, 3rd, Muller-Reichert T, Shevchenko A, Oegema K, Hyman AA (2007)

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The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions. FEBS Letters 581: 4450-4454.

Kowalinski E, Bange G, Bradatsch B, Hurt E, Wild K, Sinning I. (2007)

The crystal structure of Ebp1 reveals how the methionine aminopeptidase fold serves as a binding platform for multiple interactions. FEBS Lett. 581, 4450-4454.

Eva Kowalinski, Gert Bange, Bettina Bradatsch, Ed Hurt, Klemens Wild and Irmi Sinning (2007)

The crystal structure of the third SRP GTPase FlhF reveals a homodimer with bound GTP. Proc. Natl. Acad.Sci. USA 104: 13621-13625.

Bange G, Petzold G, Wild K, Parlitz RO, Sinning I. (2007)

The structure of the chloroplast signal recognition particle (SRP) receptor reveals mechanistic details of SRP GTPase activation and a conserved membrane targeting site. FEBS Letters 581:5671-6.

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Neuwirth M, Flicker K, Strohmeier M, Tews I, Macheroux P. (2007)

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Roig J, Krause JM, Berger P, Merz WE. (2007)

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Fitzpatrick TB, Amrhein N, Kappes B, Macheroux P, Tews I, Raschle T. (2007)

Unconventional Protein Secretion: An Extracellular Trap For Nonclassical Export of Fibroblast Growth Factor 2. J. Cell Sci. 120:2295-2299.

Walter Nickel (2007)

Vascular and Neural development, intersecting parallelisms and crossroads. Book chapter for the book titled: Therapeutic Neovascularization-Quo Vadis?. Edited by Deindl and Kupatt. Springer 159-191.

Zacchigna, S, Ruiz de Almodovar, C, Lafuste, P & Carmeliet, P. (2007)

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A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme. J Am Chem Soc. 128(33):10784-94.

Bauer H, Fritz-Wolf K, Winzer A, Kühner S, Little S, Yardley V, Vezin H, Palfey B, Schirmer RH, Davioud-Charvet E. (2006)

A fluoro analogue of the menadione derivative 6-[2’-(3’-Methyl)-1’,4’-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme. J. Am. Chem. Soc. 128:10784–94.

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Thorsten Schäfer, Bohumil Maco, Elisabeth Petfalski, David Tollervey, Bettina Boettcher, Ueli Aebi and Ed Hurt (2006)

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Cell surface heparan sulfate proteoglycans are essential components of the unconventional export machinery of FGF-2. Proc. Natl. Acad Sci. U.S.A. 103:15479-15484.

Christoph Zehe, André Engling, Sabine Wegehingel, Tobias Schäfer, and Walter Nickel (2006)

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Béthune, J*, Kol, M, Hoffmann, J, Reckmann, I, Brugger, B, and Wieland, F* (2006)

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Béthune J, Kol M, Hoffmann J, Reckmann I, Brügger B, Wieland F. (2006)

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J. Béthune, M. Kol, J. Hoffmann, I. Reckmann, B. Brügger, F. Wieland (2006)

Controversy fuels trafficking of GPI-anchored proteins. Journal of Cell Biology. Commentary (abstract)

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Ulrike Hardeland and Ed Hurt (2006)

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Béthune, J*, Wieland, F, and Moelleken, J (2006)

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J. Béthune, F. Wieland, J. Moelleken (2006)

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Schuck, S., Honsho, M., & Simons, K. (2006)

Eosin B as a novel antimalarial agent for drug-resistant Plasmodium falciparum. Antimicrob Agents Chemother. 50(9):3132-41.

Massimine KM, McIntosh MT, Doan LT, Atreya CE, Gromer S, Sirawaraporn W, Elliott DA, Joiner KA, Schirmer RH, Anderson KS. (2006)

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Halic M, Blau M, Becker T, Mielke T, Pool MR, Wild K, Sinning I, Beckmann R. (2006)

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