RESEARCH GROUPS
PAGES
GENERAL PAGES
Groupleader: Rob Russell
Lab Members
Magdalena Georgieva
PhD student
PhD student
/ Phone: +49 6221 54-51 360
Mail:Magdalena.Georgieva@bioquant.uni-heidelberg.de
Gurdeep Singh
PhD student
PhD student
Lab:Room INF 267, R 562
/ Phone: +49 6221 54-51360
Mail:gurdeep.singh@bioquant.uni-heidelberg.de
Publications
Biochemically validated structural model of the 15-subunit intraflagellar transport complex IFT-B. The EMBO journal, 41(24), e112440. https://doi.org/10.15252/embj.2022112440
Petriman, N. A., Loureiro-López, M., Taschner, M., Zacharia, N. K., Georgieva, M. M., Boegholm, N., Wang, J., Mourão, A., Russell, R. B., Andersen, J. S., & Lorentzen, E. (2022)
Never-homozygous genetic variants in healthy populations are potential recessive disease candidates. npj Genom. Med. 7, 54. https://doi.org/10.1038/s41525-022-00322-z. Schmenger, T., Diwan, G. D., Singh, G., Apic, G., & Russell, R. B. (2022)
PRECOGx: exploring GPCR signaling mechanisms with deep protein representations. Nucleic acids research, 50(W1), W598–W610. https://doi.org/10.1093/nar/gkac426 Matic, M., Singh, G., Carli, F., De Oliveira Rosa, N., Miglionico, P., Magni, L., Gutkind, J. S., Russell, R. B., Inoue, A., & Raimondi, F (2022)
The human signal peptidase complex acts as a quality control enzyme for membrane proteins. Science. 2022 Dec 2;378(6623):996-1000. doi: 10.1126/science.abo5672. Epub 2022 Dec 1. PMID: 36454823. Zanotti A, Coelho JPL, Kaylani D, Singh G, Tauber M, Hitzenberger M, Avci D, Zacharias M, Russell RB, Lemberg MK, Feige MJ (2022)
The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes. PloS one, 17(8), e0261543. https://doi.org/10.1371/journal.pone.0261543 Porcellato, E., González-Sánchez, J. C., Ahlmann-Eltze, C., Elsakka, M. A., Shapira, I., Fritsch, J., Navarro, J. A., Anders, S., Russell, R. B., Wieland, F. T., & Metzendorf, C. (2022)
Mechnetor: a web server for exploring protein mechanism and the functional context of genetic variants. Nucleic Acids Res. 2021 Jul 2;49(W1):W366-W374. doi: 10.1093/nar/gkab399. PMID: 34076240
González-Sánchez JC, Ibrahim MFR, Leist IC, Weise KR, Russell RB (2021)
Next Generation Protein Structure Predictions and Genetic Variant Interpretation. J Mol Biol. 2021 Oct 1;433(20):167180. doi: 10.1016/j.jmb.2021.167180. Epub 2021 Aug 4. PMID: 34358547
Diwan GD, Gonzalez-Sanchez JC, Apic G, Russell RB (2021)
RhoGAP19D inhibits Cdc42 laterally to control epithelial cell shape and prevent invasion. J Cell Biol. 2021 Apr 5;220(4):e202009116. doi: 10.1083/jcb.202009116. PMID: 33646271
Fic W, Bastock R, Raimondi F, Los E, Inoue Y, Gallop JL, Russell RB, St Johnston D (2021)
The Interaction of Munc18-1 Helix 11 and 12 with the Central Region of the VAMP2 SNARE Motif Is Essential for SNARE Templating and Synaptic Transmission. eNeuro, 7(6), ENEURO.0278-20.2020. https://doi.org/10.1523/ENEURO.0278-20.2020 André, T., Classen, J., Brenner, P., Betts, M. J., Dörr, B., Kreye, S., Zuidinga, B., Meijer, M., Russell, R. B., Verhage, M., & Söllner, T. H. (2020)
Never-homozygous genetic variants in healthy populations are potential recessive disease candidates. npj Genom. Med. 7, 54. https://doi.org/10.1038/s41525-022-00322-z. Schmenger, T., Diwan, G. D., Singh, G., Apic, G., & Russell, R. B. (2022)
PRECOGx: exploring GPCR signaling mechanisms with deep protein representations. Nucleic acids research, 50(W1), W598–W610. https://doi.org/10.1093/nar/gkac426 Matic, M., Singh, G., Carli, F., De Oliveira Rosa, N., Miglionico, P., Magni, L., Gutkind, J. S., Russell, R. B., Inoue, A., & Raimondi, F (2022)
The human signal peptidase complex acts as a quality control enzyme for membrane proteins. Science. 2022 Dec 2;378(6623):996-1000. doi: 10.1126/science.abo5672. Epub 2022 Dec 1. PMID: 36454823. Zanotti A, Coelho JPL, Kaylani D, Singh G, Tauber M, Hitzenberger M, Avci D, Zacharias M, Russell RB, Lemberg MK, Feige MJ (2022)
The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes. PloS one, 17(8), e0261543. https://doi.org/10.1371/journal.pone.0261543 Porcellato, E., González-Sánchez, J. C., Ahlmann-Eltze, C., Elsakka, M. A., Shapira, I., Fritsch, J., Navarro, J. A., Anders, S., Russell, R. B., Wieland, F. T., & Metzendorf, C. (2022)
Mechnetor: a web server for exploring protein mechanism and the functional context of genetic variants. Nucleic Acids Res. 2021 Jul 2;49(W1):W366-W374. doi: 10.1093/nar/gkab399. PMID: 34076240
González-Sánchez JC, Ibrahim MFR, Leist IC, Weise KR, Russell RB (2021)
Next Generation Protein Structure Predictions and Genetic Variant Interpretation. J Mol Biol. 2021 Oct 1;433(20):167180. doi: 10.1016/j.jmb.2021.167180. Epub 2021 Aug 4. PMID: 34358547
Diwan GD, Gonzalez-Sanchez JC, Apic G, Russell RB (2021)
RhoGAP19D inhibits Cdc42 laterally to control epithelial cell shape and prevent invasion. J Cell Biol. 2021 Apr 5;220(4):e202009116. doi: 10.1083/jcb.202009116. PMID: 33646271
Fic W, Bastock R, Raimondi F, Los E, Inoue Y, Gallop JL, Russell RB, St Johnston D (2021)
The Interaction of Munc18-1 Helix 11 and 12 with the Central Region of the VAMP2 SNARE Motif Is Essential for SNARE Templating and Synaptic Transmission. eNeuro, 7(6), ENEURO.0278-20.2020. https://doi.org/10.1523/ENEURO.0278-20.2020 André, T., Classen, J., Brenner, P., Betts, M. J., Dörr, B., Kreye, S., Zuidinga, B., Meijer, M., Russell, R. B., Verhage, M., & Söllner, T. H. (2020)
Contact
Heidelberg University
Biochemistry Center (BZH)
Im Neuenheimer Feld 328
69120 Heidelberg
Biochemistry Center (BZH)
Im Neuenheimer Feld 328
69120 Heidelberg
Office:
+49 6221 54-51 362 Fax:
+49 6221 54-51 486 E-Mail:
robert.russell@bioquant.uni-heidelberg.de