Lab:Room 223
/ Phone: +49 6221 54-4735
Mail:timon.andre@bzh.uni-heidelberg.de
Room | Phone | |
---|---|---|
LAB | 223 | +49 6221 54-4735 |
timon.andre@bzh.uni-heidelberg.de |
Lab:Room 221
/ Phone: +49 6221 54-5343
Mail:lara.braun@bzh.uni-heidelberg.de
Room | Phone | |
---|---|---|
LAB | 221 | +49 6221 54-5343 |
lara.braun@bzh.uni-heidelberg.de |
Lab:Room 222
/ Phone: +49 6221 54-5344
Mail:philipp.brenner@bzh.uni-heidelberg.de
Room | Phone | |
---|---|---|
LAB | 222 | +49 6221 54-5344 |
philipp.brenner@bzh.uni-heidelberg.de |
Lab:Room 222
/ Phone: +49 6221 54-5344
Mail:eda.demirel@bzh.uni-heidelberg.de
Room | Phone | |
---|---|---|
LAB | 222 | +49 6221 54-5344 |
eda.demirel@bzh.uni-heidelberg.de |
Office:Room 205
/ Phone: +49 6221 54-5340
Mail:martina.franke@bzh.uni-heidelberg.de
Sekr. Söllner 2.OG: 6:45 - 11:00 Uhr
Sekr. Brunner 5. OG: 11:00 - 14:30 Uhr
Sekr. Söllner 2.OG: 14:30 - 15:15 Uhr
Room | Phone | |
---|---|---|
OFFICE | 205 | +49 6221 54-5340 |
martina.franke@bzh.uni-heidelberg.de |
Lab:Room 221
/ Phone: +49 6221 54-5343
Mail:uschi.goebel@bzh.uni-heidelberg.de
Room | Phone | |
---|---|---|
LAB | 221 | +49 6221 54-5343 |
uschi.goebel@bzh.uni-heidelberg.de |
Lab:Room 221
/ Phone: +49 6221 54-5343
Office:Room 201
/ Phone: +49 6221 54-5345
Mail:joerg.malsam@bzh.uni-heidelberg.de
Room | Phone | |
---|---|---|
LAB | 221 | +49 6221 54-5343 |
OFFICE | 201 | +49 6221 54-5345 |
joerg.malsam@bzh.uni-heidelberg.de |
Lab:Room 221
/ Phone: +49 6221 54-5343
Mail:jacqueline.murach@bzh.uni-heidelberg.de
Room | Phone | |
---|---|---|
LAB | 221 | +49 6221 54-5343 |
jacqueline.murach@bzh.uni-heidelberg.de |
Lab:Room 222
/ Phone: +49 6221 54-5344
Mail:kerstin.rink@bzh.uni-heidelberg.de
Room | Phone | |
---|---|---|
LAB | 222 | +49 6221 54-5344 |
kerstin.rink@bzh.uni-heidelberg.de |
Lab:Room 221
/ Phone: +49 6221 54-5343
Mail:andrea.scheutzow@bzh.uni-heidelberg.de
Room | Phone | |
---|---|---|
LAB | 221 | +49 6221 54-5343 |
andrea.scheutzow@bzh.uni-heidelberg.de |
1980 - 1981 | Study of biology at the University of Regensburg |
1982 - 1986 | Study of biology at the Ludwig-Maximilians University Munich |
1987 - 1991 |
Ph.D. student at the Ludwig-Maximilians University Munich (laboratory of Prof. Dr. Dr. Walter Neupert) |
1991 – 1993 |
Post-doctoral fellow at Sloan-Kettering Institute, New York, USA (laboratory of Prof. Dr. James E. Rothman) |
1994 - 1997 |
Assistant Laboratory Member at Sloan-Kettering Institute, New York, USA (laboratory of Prof. Dr. James E. Rothman) |
1998 - 2004 |
Assistant Member (Assistant Professor) at Sloan-Kettering Institute, New York, USA |
2004 - 2005 |
Associate Member (Associate Professor) at Sloan-Kettering Institute, New York, USA |
since 15.09.2005 |
Professor at the University of Heidelberg (BZH) |
2016 - 2018 | Director of the Heidelberg University Biochemistry Center (BZH) |
2012
Malsam, J., Parisotto, D., Bharat, T.A., Scheutzow A., Krause, J.M., Briggs, J.A., Söllner, T.H. (2012) Complexin arrests a pool of docked vesicles for fast Ca (2+)-dependent release. EMBO J. 31, 3270-3281
Parisotto, D., Malsam, J., Scheutzow, A., Krause, J.M., Söllner, T.H. (2012) SNAREpin Assembly by Munc18-1 Requires Previous Vesicle Docking by Synaptotagmin 1. J. Biol. Chem. 287, 31041-31049
2011
Schollmeier, Y., Krause, J. M., Kreye, S., Malsam, J., Söllner, T.H. (2011). Resolving the Function of Distinct Munc18-1/SNARE Protein Interaction Modes in a Reconstituted Membrane Fusion. JBC 286 No. 35, 30582-30590.
Malsam, J., and Söllner, T.H. (2011). Organization of SNAREs within the Golgi stack. in ‘The Golgi’, Coldspring Harbor Perspectives in Biology (editors Warren, G. and Rothman, J.) Cold Spring Harbor Laboratory Press
2010
Kögel, T., Rudolf, R., Hodneland, E., Hellwig, A., Kuznetsov, S., Seiler, F., Söllner, T.H., Barroso, J., Gerdes, H.-H. (2010). Distinct Roles of Myosin Va in Membrane Remodeling and Exocytosis of Secretory Granules. Traffic, 11: 637-650.
2009
Seiler, F., Malsam, J., Krause, JM., Söllner, T.H. (2009). A role of complexin-lipid interactions in membrane fusion. FEBS letters, 583: 2343-8.
Malsam, J., Seiler, F., Schollmeier, Y., Rusu, P., Krause, JM., Söllner, T.H. (2009). The carboxy-terminal domain of complexin I stimulates liposome fusion. Proc. Natl. Acad. Sci. USA, 106: 2001-2006.
2008
Malsam, J., Kreye, S., Söllner, T.H. (2008). Membrane fusion: SNAREs and regulation. Cell Mol. Life. Sci., 65: 2814-2832.
Kreye, S., Malsam, J., Söllner, T.H. (2008). In vitro assays to measure SNARE mediated membrane fusion. Methods in Mol. Biol. 440: 37-50.
2007
Moelleken, J., Malsam, J., Betts, M.J., Movafeghi, A., Reckmann, I., Meissner, I., Hellwig, A., Russell, R.B., Söllner, T.H., Brügger, B., Wieland, F.T. (2007). Differential localization of isoformic coatomer complexes within the Golgi apparatus. Proc. Natl. Acad. Sci. USA, 104: 4425-30.
Söllner, T.H. (2007). Membrane trafficking. FEBS Letters, 581: 2075.
Söllner, T.H. (2007). Lipid droplets highjack SNAREs. Nat. Cell Biol., 9:1219-20.
2005
Cosson, P., Ravazzola, M., Varlamov, O., Söllner, T.H., Di Liberto, M., Volchuk, A., Rothman J.E., Orci, L. (2005). Dynamic transport of SNARE proteins in the Golgi apparatus. Proc Natl Acad Sci U S A, 102:14647-52.
2004
Cheng, Y. Sequeira, S.M., Malinina, L., Tereshko, V., Söllner, T.H., and Patel, D.J. (2004). Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain. Protein Science, 13: 2665-2672.
Söllner, T.H. (2004) Intracellular and viral membrane fusion: a uniting mechanism. Curr. Opinion Cell Biol, 16: 429-435.
Fukasawa, M., Varlamov, O., Eng, W.S., Söllner, T.H., and Rothman, J.E. (2004). Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation. Proc. Natl. Acad. Sci. USA, 101: 4815-1820.
Varlamov, O., Volchuk, A., Rahimian, V., Doege, C.A. Paumet, F., Eng, W.S, Arango, N.C., Parlati, F., Ravazzola, M., Orci, L, Söllner, T.H., and Rothman, J.E. (2004). i-SNAREs, inhibitory SNAREs that fine-tune the specificity of membrane fusion. J. Cell Biol., 164: 79-88.
2003
Söllner, T.H., and Sequeira, S. (2003) S-nitrosylation of NSF controls membrane trafficking. Cell, 115: 127-129.
Burri, L., Varlamov, O., Doege, C., Hofman, K., Beilharz, T., Rothman, J.E., Söllner, T.H., and Lithgow, T. (2003). A SNARE required for retrograde transport to the endoplasmic reticulum. Proc. Natl. Acad. Sci. USA, 100: 9873-9877.
Hu, C., Ahmed, M., Melia, T.J., Söllner, T.H., Mayer, T., and Rothman, J.E. (2003). Fusion of cells by flipped SNAREs. Science, 300: 1745-1749.
Söllner T.H. (2003). Regulated exocytosis and SNARE function. Mol. Memb. Biol., 20: 209-220.
Mahal, L.K., Sequeira, S.M., Gureasko, J., and Söllner, T.H. (2002). Calcium-independent stimulation of membrane fusion and SNAREpin formation by synaptotagmin I. J.Cell Biol., 158: 273-282.
2002
Parlati, F., Varlamov, O., Paz, K., McNew, J.A., Hurtado, D., Söllner, T.H., and Rothman, J.E. (2002). Distinct SNARE complexes mediating membrane fusion in Golgi
transport based on combinatorial specificity. Proc. Natl. Acad. Sci. USA, 99: 5424-5429.
Melia, T.J., Weber, T., McNew, J.A., Fisher, L.E., Johnston, R.J., Parlati, F., Mahal, L.K. Söllner, T.H., and Rothman, J.E. (2002). Regulation of membrane fusion by the membrane-proximal coil of the t SNARE during zippering of SNAREpins. J. Cell Biol, 158: 929-940.
2000
McNew, J.A., Parlati, F., Fukuda, R., Johnston, R.J., Paz, K., Paumet, F., Söllner, T.H., and Rothman, J.E. (2000). Compartmental specificity of cellular membrane fusion encoded in SNARE proteins. Nature, 407: 153-159.
Parlati, F., McNew, J.E., Fukuda, R., Miller, R., Söllner, T.H., and Rothman, J.E. (2000). Topological restriction of SNARE-dependent membrane fusion. Nature, 407: 194-198.
Fukuda, R., McNew, J.A., Weber, T., Parlati, F., Engel, T., Nickel, W., Rothman, J.E., and Söllner, T.H. (2000) Functional architecture of an intracellular membrane t-SNARE. Nature, 407: 198-202.
Brügger, B., Nickel, W., Weber, T., Parlati, F., McNew, J.A., Rothman, J.E. and Söllner, T. (2000). Putative fusogenic activity of NSF is restricted to a lipid mixture whose coalescence is also triggered by other factors. EMBO J., 19: 1272-1278.
McNew, J.A., Weber, T., Parlati, F., Johnston, R., Melia, T.J., Söllner, T.H., and Rothman, J.E. (2000). Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors. J.Cell Biol., 150: 105-117.
Weber, T., Parlati, F., McNew, J.A., Johnston, R.J., Westermann, B., Söllner, T.H., and Rothman, J.E. (2000). SNAREpins are functionally resistant to disruption by NSF and aSNAP. J.Cell Biol., 149: 1063-1072.
1993-1998
Hohl., T.M., Parlati, F., Wimmer, C., Rothman, J.E., Söllner, T.H., and Engelhardt, H. (1998). Arrangement of subunits in 20 S particles consisting of NSF, SNAPs, and SNARE complexes. Mol. Cell, 2: 539-548.
Weber, T., Zemelman, B.V., McNew, J.A., Westermann, B., Gmachl, M., Parlati, F., Söllner, T.H., and Rothman, J.E. (1998). SNAREpins: minimal machinery for membrane fusion. Cell, 92: 759-772.
Rothman, J.E., and Söllner, T.H. (1997). Throttles and Dampers: controlling the engine of membrane fusion. Science, 276: 1212-1213.
Nagahama, M., Orci, L., Ravazzola, M., Amherdt, M., Lacomis, L., Tempst, P., Rothman, J.E., and Söllner, T.H. (1996). A v-SNARE implicated in intra-Golgi transport. J. Cell. Biol, 133: 507-516
Søgaard, M., Tani, K., Ye, R.R., Geromanos, S., Tempst, T., Kirchausen, T., Rothman, J.E., and Söllner, T. (1994). A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. Cell, 78: 937-948.
Söllner, T., Bennett, M.K., Whiteheart, S.W., Scheller, R.H., and Rothman, J.E. (1993). A protein assembly - disassembly pathway that may correspond to sequential steps of synaptic vesicle docking, activation and fusion. Cell, 75: 409-418.
Söllner, T., Whiteheart, S.W., Brunner, M., Erdjument-Bromage, H., Geromanos, S., Tempst, P., and Rothman, J.E. (1993). SNAP receptors implicated in vesicle targeting and fusion. Nature, 362: 318-324.