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TRR Teilprojekte
Project 1Specific interactions of lipids with protein transmembrane segments
Principal investigators:
PD Dr. Britta Brügger
Heidelberg University Biochemistry Center
britta.bruegger@bzh.uni-heidelberg.de
Prof. Dr. Felix Wieland
Heidelberg University Biochemistry Center
felix.wieland@bzh.uni-heidelberg.de
Project 2
Analysis of lipids and lipid-protein interactions in living cells
Principal investigator:
PD Dr. Carsten Schultz
European Molecular Biology Laboratory (EMBL)
schultz@embl.de
Project 3
Lipid-protein interactions in rafts
Principal investigator:
Prof. Dr. Kai Simons
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden
simons@mpi-cbg.de
Project 4
High-resolution imaging the assembly and probing the interactions of human receptors in different sphingolipid-cholesterol assemblies
Principal investigator:
Prof. Dr. Daniel Müller
BIOTEC, TU Dresden
mueller@biotec.tu-dresden.de
Project 5
Microdomain-dependent trafficking of Src kinases
Principal investigator:
Prof. Dr. Walter Nickel
Heidelberg University Biochemistry Center
walter.nickel@bzh.uni-heidelberg.de
Project 6
Prominin/membrane-lipid assemblies and their relevance for apical plasma membrane protrusions
Principal investigators:
Dr. Denis Corbeil
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden
denis.corbeil@biotec.tu-dresden.de
Prof. Dr. Wieland Huttner
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden
HUTTNER@mpi-cbg.de
Project 7
Characterization of saposin-dependent microdomains in inner lysosomal membranes of Drosophila
Principal investigators:
Prof Dr. Michael Hoch
Life & Medical Sciences Institute (LIMES) University of Bonn
m.hoch@uni-bonn.de
Prof. Dr. Konrad Sandhoff
Life & Medical Sciences Institute (LIMES) University of Bonn
sandhoff@uni-bonn.de
Project 8
Protein-lipid interactions during the formation of clathrin/AP-1-coated transport intermediates: implication of the BAR domain-containing Arfaptin1/2
Principal investigator:
Prof. Dr. Bernhard Hoflack
BIOTEC, TU Dresden
Bernard.Hoflack@biotec.tu-dresden.de
Project 9
Investigating the role of local curvature in recruiting membrane sculpting proteins in vitro
Principal investigator:
Prof. Dr. Petra Schwille
BIOTEC, TU Dresden
schwille@biotec.tu-dresden.de
Project 10
The role of membrane microdomains in membrane fusion
Principal investigator:
Prof. Dr. Thomas Söllner
Heidelberg University Biochemistry Center
thomas.soellner@bzh.uni-heidelberg.de
Project 11
Role of lipids in the organization and function of exocytotic membrane domains
Principal investigator:
Prof. Dr. Thorsten Lang
Life & Medical Sciences Institute (LIMES) University of Bonn
thorsten.lang@uni-bonn.de
Project 12
Structure and assembly of the lipid droplet surface
Principal investigator:
Prof. Dr. Christoph Thiele
Life & Medical Sciences Institute (LIMES) University of Bonn
cthiele@uni-bonn.de
Project 13
Structural and functional studies of lipid droplets and their role in hepatitis C virus assembly
Principal investigator:
Prof. Dr. Ralf Bartenschlager
Department of Molecular Virology, University Hospital Heidelberg
ralf_bartenschlager@med.uni-heidelberg.de
Project 14
Lipid composition of HIV-1 and its relevance for particle formation, stability and infectivity
Principal investigator:
Prof. Dr. Hans-Georg Kräusslich
Department of Virology, Institute for Hygiene, University Hospital Heidelberg
hans-georg.kraeusslich@med.uni-heidelberg.de
Project 15
Membrane microdomain interactions of the HIV-1 pathogenicity factor Nef
Principal investigator:
Prof. Dr. Oliver Fackler
Department of Virology, Institute for Hygiene, University Hospital Heidelberg
oliver.fackler@med.uni-heidelberg.de
Project 16
Identification and functional characterization of proteins associated with membrane fractions surrounding activating and inhibitory Natural Killer cell receptors
Principal investigator:
Prof. Dr. Carsten Watzl
Institute for Immunology, University Hospital Heidelberg
watzl@uni-hd.de
Project 17
Shotgun Lipidomics on Hybrid Tandem Mass Spectrometers
Principal investigator:
Dr. Andrej Shevchenko
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden
shevchenko@mpi-cbg.de
