Research Group Leaders

Britta Brügger

Modulation of protein activities by interactions with lipids & Lipidomics

Michael Brunner

Circadian Rhythms and Molecular Clocks

Mandy Jeske

piRNA biogenesis and function

Fabio Lolicato

Membrane Biophysics

Michael Meinecke

Molecular Membrane Biology

Joachim Moser von Filseck

Molecular mechanisms of membrane remodelling

Walter Nickel

Unconventional Protein Secretion

Cristina Paulino

Structural Biology & Mechanism of Membrane Transporters and Channels

Jirka Peschek

RNA Processing and Repair

Anne Schlaitz

Organelle Dynamics during Mitosis

Sebastian Schuck

Organelle Homeostasis

Irmgard Sinning

Structural Biology

Thomas Söllner

Regulated Membrane Fusion: Molecular Mechanisms and Machinery

News

New Publication from Sinning Group: Pseudouridine increases ribosome stability in a thermophilic eukaryote.
January 13, 2026
New Publication from Sinning Group: NatA engages in multi-factor complexes at the ribosomal polypeptide tunnel exit.
February 4, 2026
DFG grants a second funding period of the Collaborative Research Center SFB/TRR 319: RNA Modification and Processing in Mainz-Heidelberg
December 5, 2025
DFG grants a third funding period of the Collaborative Research Center SFB 1324: Mechanisms and functions of Wnt signaling in Heidelberg.
December 5, 2025
New Publication from Sinning Group: Structural characterisation of the fungal Pmt4 homodimer.
December 19, 2025
New Publication from Schuck Group: Dynamic Organellar Mapping in yeast reveals extensive protein localization changes during ER stress
December 2, 2025
New publication from Lolicato and Nickel groups in Nature Commun.
November 29, 2025
Dr. Jirka Peschek receives 2025 Chica and Heinz Schaller Award
November 10, 2025
New Publication from Peschek Group: Structural Insights into RNA Repair Enzymes
September 9, 2025
New Publication from Hurt Group: Structural insights into spliceosome fidelity: DHX35–GPATCH1- mediated rejection of aberrant splicing substrates
April 7, 2025
New Publication from Schuck Group: Reprograming of the ubiquitin ligase Ubr1 by intrinsically disordered Roq1 through cooperating multifunctional motifs
February 18, 2025
New Publication from Sinning Group: Insights into splicing quality control: how cells avoid errors in the production of mRNA
January 27, 2025
We welcome our guest Professor Randy Stockbridge from the University of Michigan, USA, at the BZH
November 22, 2024
PaLMe Teaching Award for Sebastian Schuck
November 6, 2024
Dr. Mandy Jeske receives 2024 Chica and Heinz Schaller Award
October 10, 2024
DFG funds new Collaborative Research Center SFB 1638 in Heidelberg
July 23, 2024
DFG grants a third funding period of the Collaborative Research Centre SFB/TRR 186 Berlin-Heidelberg
May 31, 2024

Research Group Leaders

Britta Brügger

Modulation of protein activities by interactions with lipids & Lipidomics

Michael Brunner

Circadian Rhythms and Molecular Clocks

Mandy Jeske

piRNA biogenesis and function

Fabio Lolicato

Membrane Biophysics

Michael Meinecke

Molecular Membrane Biology

Joachim Moser von Filseck

Molecular mechanisms of membrane remodelling

Walter Nickel

Unconventional Protein Secretion

Cristina Paulino

Structural Biology & Mechanism of Membrane Transporters and Channels

Jirka Peschek

RNA Processing and Repair

Anne Schlaitz

Organelle Dynamics during Mitosis

Sebastian Schuck

Organelle Homeostasis

Irmgard Sinning

Structural Biology

Thomas Söllner

Regulated Membrane Fusion: Molecular Mechanisms and Machinery

News

New Publication from Sinning Group: Pseudouridine increases ribosome stability in a thermophilic eukaryote.
January 13, 2026
New Publication from Sinning Group: NatA engages in multi-factor complexes at the ribosomal polypeptide tunnel exit.
February 4, 2026
DFG grants a second funding period of the Collaborative Research Center SFB/TRR 319: RNA Modification and Processing in Mainz-Heidelberg
December 5, 2025
DFG grants a third funding period of the Collaborative Research Center SFB 1324: Mechanisms and functions of Wnt signaling in Heidelberg.
December 5, 2025
New Publication from Sinning Group: Structural characterisation of the fungal Pmt4 homodimer.
December 19, 2025
New Publication from Schuck Group: Dynamic Organellar Mapping in yeast reveals extensive protein localization changes during ER stress
December 2, 2025
New publication from Lolicato and Nickel groups in Nature Commun.
November 29, 2025
Dr. Jirka Peschek receives 2025 Chica and Heinz Schaller Award
November 10, 2025
New Publication from Peschek Group: Structural Insights into RNA Repair Enzymes
September 9, 2025
New Publication from Hurt Group: Structural insights into spliceosome fidelity: DHX35–GPATCH1- mediated rejection of aberrant splicing substrates
April 7, 2025
New Publication from Schuck Group: Reprograming of the ubiquitin ligase Ubr1 by intrinsically disordered Roq1 through cooperating multifunctional motifs
February 18, 2025
New Publication from Sinning Group: Insights into splicing quality control: how cells avoid errors in the production of mRNA
January 27, 2025
We welcome our guest Professor Randy Stockbridge from the University of Michigan, USA, at the BZH
November 22, 2024
PaLMe Teaching Award for Sebastian Schuck
November 6, 2024
Dr. Mandy Jeske receives 2024 Chica and Heinz Schaller Award
October 10, 2024
DFG funds new Collaborative Research Center SFB 1638 in Heidelberg
July 23, 2024
DFG grants a third funding period of the Collaborative Research Centre SFB/TRR 186 Berlin-Heidelberg
May 31, 2024

Research Group Leaders

Britta Brügger

Modulation of protein activities by interactions with lipids & Lipidomics

Michael Brunner

Circadian Rhythms and Molecular Clocks

Mandy Jeske

piRNA biogenesis and function

Fabio Lolicato

Membrane Biophysics

Michael Meinecke

Molecular Membrane Biology

Joachim Moser von Filseck

Molecular mechanisms of membrane remodelling

Walter Nickel

Unconventional Protein Secretion

Cristina Paulino

Structural Biology & Mechanism of Membrane Transporters and Channels

Jirka Peschek

RNA Processing and Repair

Anne Schlaitz

Organelle Dynamics during Mitosis

Sebastian Schuck

Organelle Homeostasis

Irmgard Sinning

Structural Biology

Thomas Söllner

Regulated Membrane Fusion: Molecular Mechanisms and Machinery

News

New Publication from Sinning Group: Pseudouridine increases ribosome stability in a thermophilic eukaryote.
January 13, 2026
New Publication from Sinning Group: NatA engages in multi-factor complexes at the ribosomal polypeptide tunnel exit.
February 4, 2026
DFG grants a second funding period of the Collaborative Research Center SFB/TRR 319: RNA Modification and Processing in Mainz-Heidelberg
December 5, 2025
DFG grants a third funding period of the Collaborative Research Center SFB 1324: Mechanisms and functions of Wnt signaling in Heidelberg.
December 5, 2025
New Publication from Sinning Group: Structural characterisation of the fungal Pmt4 homodimer.
December 19, 2025
New Publication from Schuck Group: Dynamic Organellar Mapping in yeast reveals extensive protein localization changes during ER stress
December 2, 2025
New publication from Lolicato and Nickel groups in Nature Commun.
November 29, 2025
Dr. Jirka Peschek receives 2025 Chica and Heinz Schaller Award
November 10, 2025
New Publication from Peschek Group: Structural Insights into RNA Repair Enzymes
September 9, 2025
New Publication from Hurt Group: Structural insights into spliceosome fidelity: DHX35–GPATCH1- mediated rejection of aberrant splicing substrates
April 7, 2025
New Publication from Schuck Group: Reprograming of the ubiquitin ligase Ubr1 by intrinsically disordered Roq1 through cooperating multifunctional motifs
February 18, 2025
New Publication from Sinning Group: Insights into splicing quality control: how cells avoid errors in the production of mRNA
January 27, 2025
We welcome our guest Professor Randy Stockbridge from the University of Michigan, USA, at the BZH
November 22, 2024
PaLMe Teaching Award for Sebastian Schuck
November 6, 2024
Dr. Mandy Jeske receives 2024 Chica and Heinz Schaller Award
October 10, 2024
DFG funds new Collaborative Research Center SFB 1638 in Heidelberg
July 23, 2024
DFG grants a third funding period of the Collaborative Research Centre SFB/TRR 186 Berlin-Heidelberg
May 31, 2024